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IGF I Receptor

《英文msh詞典》IGF I Receptor
[入口詞] IGF I Receptor
[主題詞] Receptor,IGF Type 1
[英文釋義] A protein-tyrosine kinase receptor that is closely related in structure to the INSULIN RECEPTOR. Although commonly referred to as the IGF-I receptor,it binds both IGF-I and IGF-II with high affinity. It is comprised of a tetramer of two alpha and two beta subunits which are derived from cleavage of a single precusor protein. The beta subunit contains an intrisic tyrosine kinase domain.

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